Being transgender in America may be hazardous to your health.

A new report in JAMA Internal Medicine characterizes a variety of health disparities between people who are transgender (that is, their gender identity is not the same as their sex at birth) and people who are cisgender (their gender identity matches their sex at birth).

Spoiler alert: There are many.

The data come from the Behavioral Risk Factor Surveillance System, a health survey sponsored by the Centers for Disease Control and Prevention. In 2014, 20 states added questions about gender identity to their survey; five more joined them the following year.

Researchers from Brigham & Women’s Hospital and Beth Israel Deaconess Medical Center, both affiliated with Harvard Medical School in Boston, examined responses from 314,450 cisgender and 1,443 transgender interviewees.

People who described themselves as transgender accounted for less than half of 1 percent of the entire sample.

Overall, the transgender people were younger, poorer, less white and more likely to be unemployed than their cisgender counterparts.

The researchers also found significant health differences between the two groups. Among them:

Transgender adults were less likely to describe themselves as healthy.

The CDC asks Americans to describe their overall health as excellent, very good, good, fair or poor.

The researchers reported that 29 percent of transgender adults rated their health as fair or poor, compared with 17 percent of cisgender adults.

Transgender adults were more likely to be overweight.

Just under 66 percent of cisgender adults had a body mass index of at least 25, qualifying them as overweight. That may sound high, but it was significantly lower than the 72 percent share for the transgender adults.

Transgender adults were more likely to be uninsured.

Nearly 21 percent of transgender adults lacked health insurance when they were surveyed. By comparison, only about 11 percent of cisgender adults did not have health insurance.

Transgender adults were more likely to let a health problem go untreated.

More than 1 in 5 transgender adults said they had let a health problem fester because they couldn’t afford to get the necessary treatment.

In contrast, 1 in 8 cisgender adults were in the same predicament.

Transgender adults were more likely to be depressed

Among the transgender adults who took the survey, 22.3 percent had been diagnosed with depression. That was significantly higher than the 18.4 percent of cisgender adults who got that diagnosis.

Transgender adults had more cognitive problems.

When asked whether they had any problems with “concentrating, remembering or making decisions,” 10 percent of cisgender and 18 percent of transgender adults answered yes.

The study authors noted that since these results were based on survey responses from only some of the states, they might not reflect the health status of transgender people across the country.

However, the results were strong enough to make one thing clear: “This study confirms that gender minority adults in the United States experience health disparities compared with their cisgender peers,” they wrote, adding that “research suggests that discrimination toward gender minorities contributes to worse health outcomes.”

The researchers called for all U.S. states and territories “to administer the CDC-approved module to provide widespread collection of gender identity data using standard, reliable questions.” They said that doing so would help to begin to eliminate the health disparities.

“Our findings signal to public health professionals and practitioners to pay attention to the health of this vulnerable population,” they wrote.