No. 2 Ohio State (11-0, 8-0 Big Ten, No. 2 CFP) at No. 3 Michigan (11-0, 8-0 Big Ten, No. 3 CFP), noon EST Saturday (FOX)

Line: Michigan by 3 1/2 according to FanDuel Sportsbook.

Series record: Michigan leads 60-52-6.

KEY MATCHUP

Michigan’s passing game vs. Ohio State’s defense: To win, the Wolverines will likely need QB J.J. McCarthy to make more plays through the air than he did the last two weeks. He was 12 of 23 for a season-low passing percentage with 141 yards passing and an interception in last week’s seven-point win at Maryland. The Buckeyes are No. 1 in FBS against the pass, second in scoring defense and third in yards allowed. CB Jordan Hancock has an INT in two of the last three games. DE J.T. Tuimoloau has a team-high four sacks and 20 tackles for losses in his three-year career.

Washington State (5-6, 2-6 Pac-12) at No. 4 Washington (11-0, 8-0 Pac-12, No. 4 CFP), 4 p.m. Saturday (FOX)

Line: Washington by 16 1/2.

Series record: Washington leads 75-33-6.

KEY MATCHUP

Washington QB Michael Penix Jr. vs. Washington State’s secondary: Penix is coming off his worst game of the season in miserable conditions at Oregon State. His Heisman Trophy campaign could use one more big stat line and the Cougars could be the victim. Last year in Pullman, Penix threw for 484 yards and had five total touchdowns. The Cougars are 101st nationally giving up 241.7 yards per game through the air, but stifled Colorado last week holding the Buffaloes to 164 yards passing. Washington State has held three straight opponents under 200 yards passing.

No. 8 Alabama (10-1, 6-1 SEC, No. 8 CFP) at Auburn (6-5, 3-4), 3:30 p.m. Saturday (CBS)

Line: Alabama by 14-1/2.

Series: Alabama leads, 49-37-1.

KEY MATCHUP

Alabama’s big-play offense against a capitalistic Auburn defense: Tide quarterback Jalen Milroe has seven touchdown passes of 40-plus yards, and wide receiver Jermaine Burton is averaging 22.1 yards per catch with six TDs. Auburn is tied with Arkansas for the SEC lead with 17 forced turnovers, including 11 interceptions, led by safety Jaylin Simpson and cornerback Keionte Scott.

North Carolina (8-3, 4-3 ACC) at North Carolina State (8-3, 5-2, No. 22 CFP), 8 p.m. Saturday (ACC Network)

Line: North Carolina by 2 1/2.

Series record: UNC leads 68-38-6.

KEY MATCHUP

UNC QB Drake Maye vs. N.C. State LB Payton Wilson: Maye and Wilson are two of the league’s top players leading units that will present tough challenges to each other. Maye is sixth in the Bowl Subdivision ranks in passing (304.9) and second in total offense (336.1) at the helm of a prolific attack (third in FBS at 514.8 yards per game). Wilson is tied for sixth nationally in tackles (11.2) and leading a defense allowing 20.2 points per game.

No. 5 Florida State (11-0, No. 5 CFP) at Florida (5-6), 7 p.m. Saturday (ESPN)

Line: Florida State by 6 1/2.

Series record: Florida leads 37-27-2.

KEY MATCHUP

Florida State’s dynamic receivers vs. Florida’s porous pass defense: Keon Coleman has 45 receptions for 615 yards and 11 touchdowns this season, and 6-foot-7 Johnny Wilson has 33 catches for 532 yards and two scores. The Gators have allowed six 100-yard receivers in their last five games, including LSU’s Brian Thomas Jr. (6-150, 2 TDs), LSU’s Malik Nabers (6-132) and Missouri’s Luther Burden III (9-158).

Kentucky (6-5) at No. 9 Louisville (10-1, No. 10 CFP ), noon Saturday (ABC)

Line: Louisville by 6 1/2.

Series: Kentucky leads, 19-15.

KEY MATCHUP

Louisville is tied for 26th nationally in scoring at 33.2 points per game and beat Miami (Florida) 38-31 last week: Quarterback Jack Plummer rang up his third three-touchdown passing game this season along with 308 yards, hitting 10 receivers. Kentucky is allowing 24.3 points and 347.8 yards per game (fourth in SEC) and must slow down an offense capable of breaking multiple big plays. Louisville looks to end a four-game series slide against rival Kentucky and win the Governor’s Cup for the first time since 2017 with 2016 Heisman Trophy winner Lamar Jackson. The Cardinals also seek their 11th win for the first time since 2012 before playing in their first ACC championship game. Kentucky has lost five of six overall but seeks its third consecutive winning regular season after falling 17-14 last week at South Carolina.

— Associated Press