More than 2,700 Maryland residents could lose their jobs as part of massive layoffs announced last week at the U.S. Department of Health & Human Services, according to the state labor department.

Going into effect May 30, the cuts were part of a drastic restructuring initiated by an executive order by President Donald Trump and implemented as part of the Department of Government Efficiency’s Workforce Optimization Initiative.

As part of the plan, HHS announced a reduction of about 10,000 full-time employees. Those layoffs included over 200 jobs in the Baltimore area, according to the state’s Department of Labor.

“The Trump Administration’s continued firings of federal workers are an affront to their years of public service and dedication to our country. These employees — many of them Marylanders — contribute not only to our nation but also to their communities and to our state,” Maryland Comptroller Brooke Lierman said in a statement. “Firing these workers does not create efficiencies. Instead, it will result in a nation that is more at risk, less healthy, and less prepared to address our national and global public health needs.

“The Trump Administration’s idea of efficiency is giving the American people a government that doesn’t function or provide the core services and protections that citizens expect.”

HHS officials said the restructuring will save taxpayers $1.8 billion annually and streamline the department’s functions.

The department said many of the HHS’s 28 divisions are redundant. The restructuring plan will consolidate them into 15 new divisions, including a new Administration for a Healthy America. It will centralize functions such as human resources, information technology, procurement, external affairs and policy. Regional offices will be reduced from 10 to five.

The staffing cuts are in addition to the roughly 10,000 department employees who opted to leave once HHS Secretary Robert F. Kennedy Jr. took office. The department had about 82,000 full-time employees in January and will have 62,000 after the cuts and buyouts are complete, according to HHS.

“We aren’t just reducing bureaucratic sprawl. We are realigning the organization with its core mission and our new priorities in reversing the chronic disease epidemic,” Kennedy said in a statement. “This Department will do more — a lot more — at a lower cost to the taxpayer. Over time, bureaucracies like HHS become wasteful and inefficient even when most of their staff are dedicated and competent civil servants.”

The areas in Maryland impacted by the job cuts consist of Baltimore City (90 cuts), Baltimore County (140), Frederick County (90), Prince George’s County (215), and Montgomery County (2,220), according to the Department of Labor.

“Reports of these layoffs by HHS are troubling,” Maryland Attorney General spokesperson Jennifer Donelan told The Baltimore Sun. “We are reviewing the matter and weighing our options.”

Maryland has taken steps to fight back against the overall cuts at HHS.

On Tuesday, the state joined 22 states in a federal lawsuit over the termination of some $11 billion in funds from the HHS. While the funding cancellation could cost billions for the affected states, Maryland could lose up to $200 million, according to a news release.

“If the funding is not restored, important state public health programs and initiatives will have to be dissolved or disbanded, including vital funding to support vaccination programs, track disease outbreaks, and alleviate health disparities,” the Maryland Office of the Attorney General said in a statement.

Baltimore Sun reporter Racquel Bazoz contributed to this article. Have a news tip? Contact Todd Karpovich at tkarpovich@baltsun.com or on X as @ToddKarpovich.