LIONS (3-5)

AT BEARS (5-3)

1 p.m. Sunday

Bears by 61/2 (O/U 44)

The Lions are going to miss Golden Tate, and they can’t stop the run, or protect Matthew Stafford, surrendering 10 sacks to the Vikings last Sunday. The Bears’ smothering defense takes charge and sets the tone. Bears 27, Lions 17

SAINTS (7-1)

AT BENGALS (5-3)

1 p.m. Sunday

Saints by 51/2 (O/U 531/2)

This could be a shootout, and the Saints have more ammunition. They aren’t quite the same away from the Superdome, and their defensive backs are a liability, but they will keep it rolling on the road. Saints 28, Bengals 20

FALCONS (4-4)

AT BROWNS (2-6-1)

1 p.m. Sunday

Falcons by 6 (O/U 51)

For the Falcons, this will have the feel of Sunday’s win over the Redskins in Washington. The Browns will keep it close for a while, but the Falcons will pull away with a superior offense that’s starting to live up to its potential. Falcons 30, Browns 24

CARDINALS (2-6)

AT CHIEFS (8-1)

1 p.m. Sunday

Chiefs by 161/2 (O/U 491/2)

Patrick Mahomes is as advertised, as he’s proving every week. There aren’t a lot of good matchups for the Cardinals, but this is a particularly bad one. The Chiefs score early and often, and Arrowhead just gets louder. Chiefs 35, Cardinals 13

PATRIOTS (7-2)

AT TITANS (4-4)

1 p.m. Sunday

Patriots by 61/2 (O/U 47)

Rookie Harold Landry is looking good coming off the edge for the Titans, and Rob Gronkowski has health issues for New England. The Patriots could struggle to score early, but still have to go with them. Patriots 24, Titans 16

REDSKINS (5-3)

AT BUCCANEERS (3-5)

1 p.m. Sunday

Buccaneers by 3 (O/U 51)

The Redskins are banged up, so they won’t run it as well as they should against the Buccaneers defense. The Bucs can score, and they’re at home. Still, this should be close.

Buccaneers 24, Redskins 20

BILLS (2-7)

AT JETS (3-6)

1 p.m. Sunday

Jets by 7 (O/U 361/2)

No matter what the Bills do at quarterback, they’re just not a good team. Quarterback Sam Darnold can’t start (foot injury), but Jets have dependable veteran Josh McCown and are at home.

Jets 23, Bills 13

JAGUARS (3-5)

AT COLTS (3-5)

1 p.m. Sunday

Colts by 3 (O/U 47)

The last time the Colts played host to the Jaguars, Jacksonville sacked Jacoby Brissett 10 times and won 27-0. The Colts have gotten better, and the Jaguars have gotten much worse.

Colts 21, Jaguars 17

CHARGERS (6-2)

AT RAIDERS (1-7)

4:05 p.m. Sunday

Chargers by 10 (O/U 50)

Two teams heading in opposite directions. Philip Rivers has played his way into the MVP conversation, and the Chargers are rounding into a really tough team. The Raiders are mailing it in. Chargers 31, Raiders 13

SEAHAWKS (4-4)

AT RAMS (8-1)

4:25 p.m. Sunday

Rams by 10 (O/U 50)

The Rams haven’t lost back-to-back games under Sean McVay, and they won’t lose here. They’ll bounce back from their loss in New Orleans and do away with a Seahawks team that looks like an 8-8 squad. Rams 34, Seahawks 21

DOLPHINS (5-4)

AT PACKERS (3-4-1)

4:25 p.m. Sunday

Packers by 10 (O/U 471/2)

The Dolphins have a good secondary. That said, they’re 1-3 away from home and facing a Packers team that’s in must-win mode. Aaron Rodgers at home in a game he badly needs to win? Go with him. Packers 28, Dolphins 20

COWBOYS (3-5)

AT EAGLES (4-4)

8:20 p.m. Sunday, NBC

Eagles by 71/2 (O/U 431/2)

As bitter as this matchup is, it’s also lopsided. The Eagles are trending up, especially with the addition of Golden Tate. The Cowboys are heading in the other direction, and linebacker Sean Lee is out. Eagles 28, Cowboys 20

GIANTS (1-7)

AT 49ERS (2-7)

8:15 p.m. Monday, ESPN

49ers by 3 (O/U 44)

Nick Mullens is a great feel-good story, but is he more than a one-game wonder? And Eli Manning is a sitting duck behind that porous Giants line. Still, the 49ers are so beat up in so many places… Giants 24, 49ers 18