TORONTO — It took only two batters for the Orioles to get settled into the 2025 season.

Adley Rutschman hit a 436-foot home run in his first at-bat and went back-to-back with Jordan Westburg in the eighth inning, Tyler O’Neill homered for his MLB-record sixth consecutive opening day and Cedric Mullins launched a pair of long balls himself to lead an offensive explosion in a 12-2 win over the Toronto Blue Jays on Thursday afternoon.

The Orioles’ six home runs set a franchise record for their most in an opening day game, eclipsing the total of four they hit in their inaugural games of the 1982 and 2006 seasons.

“Opening day is always an interesting one,” Rutschman said. “Lot of nerves flying around, but I felt like our guys did a great job of coming out ready to go and, to put up a 12-spot, that always gets us a little bit of comfort and, obviously, pitching staff did great today.”

Coming off a year in which the Orioles’ offense struggled over the second half and disappeared on the playoff stage, their young lineup entered the new season looking for a new slate. They turned the page quickly by jumping all over Blue Jays starter José Berríos and putting a runner in scoring position or better in each of the first eight innings.

Rutschman wasted little time putting them on the board with his solo shot on a 2-1 pitch in the first and O’Neill opened up a 5-0 lead with his record-extending, three-run blast two innings later.

Mullins, who has started in center field on five consecutive Orioles opening days and six of the past seven, left the yard twice with a solo home run in the fourth and a two-run blast in the seventh that put the game firmly out of hand.

“Unbelievable to see the day Rutschman, O’Neill and Mullins had. Those guys have serious power, and it was good to see those guys get off to a good start,” manager Brandon Hyde said. “Adley had a tough second half, to see him get off to that start. Cedric’s looking to have a big year this year. And what can you say about O’Neill? He’s come over and his first game with us, when you do something that’s so crazy with six [straight] opening day homers, that’s mind boggling. So just a great, great team effort today.”

The offensive outburst marked the third straight season the Orioles (1-0) have scored at least 10 runs and recorded as many hits in their season opener. Rutschman, who went 5-for-5 in his first opening day two years ago, has started to make multi-hit games in the Orioles opener an annual tradition. He pushed his career opening day numbers to 10-for-14 (.714) with three homers, nine RBIs, two walks and seven runs scored with the performance.

Zach Eflin ensured that the Orioles were just as sharp on the mound, retiring the first 10 batters he faced and pitching six innings of two-run ball. Second baseman Andrés Giménez dealt the lone blemish against him — a two-run homer in the fourth — but Eflin pitched an efficient outing. Hyde pulled him at 78 pitches after six frames, sparing his opening day starter from a heavy workload with a long season ahead.

“The cushion in the beginning, getting the runs across the board,” Eflin said of what allowed him to be so efficient. “But just having the mindset of going after guys and trusting my stuff and trying to get weak contact and stay in the game as long as possible is kind of what I stick to throughout my career. But obviously, the big run support early in the game lets me kind of work more freely in that.”

Seranthony Domínguez worked around two walks and a wild pitch to record a scoreless frame in the seventh, a troubling sign after he recorded a 19.50 ERA in spring training. But he helped keep the score intact and Keegan Akin and Bryan Baker followed with clean outings of their own to shut the door on the Blue Jays. Baker got an assist from Heston Kjerstad, who entered the game as a defensive replacement in right field and threw out Blue Jays catcher Alejandro Kirk trying to stretch a single into a double on a line drive into the corner.

Former Orioles outfielder Anthony Santander, playing his first game with the club he joined in free agency on a five-year, $92.5 million deal, went 0-for-4 at the plate.

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